THE TITRATION OF WASSERMANN REAGENTS

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Complement-Fixation Technique: II. THE TITRATION OF WASSERMANN ANTIGEN.

After material has been produced for use as an antigen in a complement fixation test it is necessary to find out if the finished product has any complement-fixing ability in the presence of a serum containing a suitable antibody. Moreover, the proposed antigen must not have any undue anticomplementary property, and the " gap" between its anticomplementary titre and its complement fixing titre m...

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Concerning the Wassermann Reaction

tionally collected and kept for some time, is a very poor control. Some positive sera give a complete fixation of the usual one or more MHD of the complement in a 1 in 200 dilution; others can do so in 1 in 5 dilution only. The margin.of variation allowed for in this control, 5 to 200, is too wide to be useful in indicating whether the antigen-antibody systems involved in the reaction of comple...

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Concerning the Wassermann Reaction

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 1914

ISSN: 0003-9926

DOI: 10.1001/archinte.1914.00070120066005